Evaluation of Vitamin D in the serum of in-hospital patients with psychosis. Retrospective study.

Introduction The reduction of vitamin D (VitD) has often been associated with pathological cognitive processes and in general various mental illnesses 2,3 . More frequent reports reduced concentrations VitD concern patients schizophrenia, however it not clarified whether this concerns the pathology itself disorder or if nutritional factors are involved 1 Objectives measurement serum hospitalized illness (schizophrenia) compared to levels people without illness. Methods were measured 45 psychiatric hospital “Dromokaiteion” (22 men 23 women) mean age 59 ±14 years. control group consisted 49 healthy subjects (24 25 a 57 years (Table 1). Serum on Architect ci4100 immunobiochemical analyzer, Abbott Laboratories Ltd, by chemiluminescent microparticle immune assay (CMIA) method according manufacturer’s instructions. statistical analysis data was done software program SPSS V.25. Results Mean values Vit (ng/ml) 15.8±10.7 15.3±12.5 male female patients, respectively. For 22.4±7.9 26.4±13.9 women. both groups statistically significantly different (men p=0.021 women p=0.006). (Table2, 3). Image: Image 2: 3: Conclusions findings study consistent those similar studies confirming low This parameter should be taken into account as its is included routine laboratory date. Further future correlate deficiency specific demographic clinical characteristics. 1. Belvederi Murri M, Respino Masotti et al. Vitamin psychosis: mini meta-analysis. Schizophr Res. 2013;150(1):235-239. doi:10.1016/j.schres.2013.07.017 2. Kalueff A, Minasyan Keisala T, Kuuslahti Miettinen S, Tuohimaa P. neuroendocrine system target for novel neurotropic drugs. CNS Neurol Disord Drug Targets. (2006) 5:363–71. doi: 10.2174/187152706784111506 3. Oudshoorn C, Mattace-Raso FU, van der Velde N, Colin EM, Cammen TJ. Higher D3 better test performance Alzheimer’s disease. Dement Geriatr Cogn Disord. (2008) 25:539–43. 10.1159/000134382 Disclosure Interest None Declared